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JNMT (September 2012) Small-Animal PET: What Is It, and Why Do We Need It?
JNMT, September 2012, Volume 40, Number 3

Small-Animal PET: What Is It, and Why Do We Need It?

Release Date: September 1, 2012
Expiration Date: September 30, 2015

JNMT, September 2012, Volume 40, Number 3

California Scope: 0.5 Imaging (I) and 0.5 Non-Imaging

Rutao Yao1, Roger Lecomte2, and Elpida S. Crawford1

1Department of Nuclear Medicine, State University of New York at Buffalo, Buffalo, New York; and 2Department of Nuclear Medicine and Radiobiology, Universite de Sherbrooke, Sherbrooke, Quebec, Canada

Small-animal PET refers to imaging of animals such as rats and mice using dedicated PET scanners. Small-animal PET has been used extensively in modern biomedical research. It provides a quantitative measure of the 3-dimensional distribution of a radiopharmaceutical administered to a live subject noninvasively. In this article, we will discuss the operational and technical aspects of small-animal PET; make some comparisons between small-animal PET and human PET systems; identify the challenges of, opportunities for, and ultimate limitations in applying small-animal PET; and discuss some representative small-animal PET applications. Education objectives: After reading this article, the technologist will be able to explain the requirements and benefits of small-animal PET in biomedical research, describe the design and general characteristics of a small-animal PET system, list and describe some of the challenges of imaging small animals, and discuss several small-animal PET applications.

Key Words: positron emission tomography (PET); animal imaging

J Nucl Med Technol 2012; 40:157–165
DOI: 10.2967/jnmt.111.098632

Continuing Education Credit Information

VOICE (Technologists)
The SNMMI, through its Verification of Involvement in Continuing Education (VOICE) program, has approved this journal article for a maximum of 1.0 continuing education hours (CEHs). VOICE-approved credit is recognized by most licensure states and by the NMTCB and ARRT as Category A credit. In order to receive CE credit, you must first complete the activity content. When completed, take the post-test assessment.  You must obtain a score of 80% to receive the CE credit.  You will have no more than 3 attempts to successfully complete the post-test. Release Date: September 1, 2012. Expiration Date: September 30, 2015. California Scope: 0.5 Imaging (I)/ 0.5 Non-Imaging (NI).

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