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JNM (April 2013) Dynamic Bone Imaging with 99mTc-Labeled Diphosphonates and 18F-NaF: Mechanisms and Applications
JNM, April 2013, Volume 54, Number 4

JNM (April 2013) Dynamic Bone Imaging with 99mTc-Labeled Diphosphonates and 18F-NaF: Mechanisms and Applications

JNM, April 2013, Volume 54, Number 4

Member Fee: Free
Non-Member Fee: $15.00

Release Date: April 1, 2013
Expiration Date: April 30, 2016

Authors
Ka Kit Wong1,2 and Morand Piert1

1Nuclear Medicine/Radiology Department, University of Michigan Hospital, Ann Arbor, Michigan; and 2Nuclear Medicine Service, Department of Veterans Affairs Health System, Ann Arbor, Michigan

Disclosure
In accordance with ACCME Revised Standards for Commercial Support and SNM Conflict-of-Interest Policy, the authors have indicated no relevant relationships that could be perceived as a real or apparent conflict of interest. Disclosure of a relationship is not intended to suggest or to condone bias but is made to provide participants with information that might be of potential importance to their evaluation of the activity.

Target Audience
This article contains information of value to nuclear medicine physicians, radiologists, nuclear medicine technologists, and clinicians utilizing skeletal imaging.

Objectives
On successful completion of this activity, participants should be able to...

  1. Appreciate the physiologic mechanisms underlying uptake of bone-seeking radiopharmaceuticals used to assess bone perfusion and turnover and note the differences between 18F-NaF and 99mTc-labeled diphosphonates.
  2. Discuss the use of bone scintigraphy for evaluation of bone viability and metabolic bone disorders and appreciate the potential role of quantitative dynamic 18F-NaF PET for evaluation of response to therapy.
  3. Discuss indications for 99mTc-labeled diphosphonate bone scans and 18F-NaF PET/CT for oncologic staging and appreciate quantitative methods on static and dynamic bone imaging as imaging biomarkers of treatment response using novel systemic therapies for metastatic castrate-resistant prostate cancer as a model.

Continuing Education Credit Information

AMA-PRA (Physician)
The Society for Nuclear Medicine and Medical Imaging, Inc. (SNMMI) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

SNMMI designates this enduring material for a maximum of 2.0 AMA PRA Category 1 CreditsTM. Physicians should claim only credit commensurate with the extent of their participation in the activity. To receive CE credit, learners must achieve a score of 80% on the post-course assessment and complete the evaluation. Release date: April 1, 2013 Expiration date: April 30, 2016.

 

ACPE (Pharmacists)
The Society for Nuclear Medicine and Molecular Imaging, Inc. (SNMMI) is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity has been designated as knowledge-based CPE. The universal program number for this enduring material is 0210-0000-13-223-H04-P. Total available credit for pharmacists is 1.0 hours or 0.10 CEUs. Release Date: April 1, 2013. Expiration Date: April 30, 2016. To receive CE credit, learners must achieve a score of 80% on the post-course assessment and complete the evaluation.

VOICE (Technologists)
The SNMMI, through its Verification of Involvement in Continuing Education (VOICE) program, has approved this journal article for a maximum of 1.0 continuing education hours (CEHs). VOICE-approved credit is recognized by most licensure states and by the NMTCB and ARRT as Category A credit. In order to receive CE credit, you must first complete the activity content. When completed, take the post-test assessment.  You must obtain a score of 80% to receive the CE credit.  You will have no more than 3 attempts to successfully complete the post-test. Release Date: April 1, 2013. Expiration Date: April 30, 2016. California Scope: 0.5 Imaging (I)/ 0.5 Radiopharmacy (R).


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